
I’m your friendly online herbalist, here to share my perspective- and that’s the first important part. Both plants and people are complicated, so the sooner you shift from the idea that you can “use” plants to the idea that you “work with” them, the easier this will go for everyone.
The idea that we can "use" herbal medicine in place of OTC (over the counter) stuff isn't exactly a mistake people make, though. We've gotten the expectation of "use" in an exploitative sense ingrained in our culture from generations of being told that someone or something else will fix it for us. Please don't get me wrong- there are definitely times when someone or something else can and should! I was an EMT and believe me, I don't dismiss Western medicine out of hand.
What I do believe is that there's still lots and lots of health and healing that we as individuals simply ARE in charge of, and responsible for. This is a radical idea if you think it through, because most of the messaging we get is that we're absolutely not, and it's why I say it's not a "mistake" to think it. It's a challenge to shift your thinking, especially when you can't quite see the whole new picture simply because of its newness.
So I'm asking you to practice this tiny step, and see where it leads you. When you start considering an herbal remedy, actively substitute "work with" every time your brain automatically says "use". That's all! Now, on to the main event- pain and herbs.

The first thing I want to say is that OTC is not evil. It is perfectly fine to reach for them when you need or want, just be aware of what else is going on! And some plants work the same way, binding with pain receptors, so the OTC actions aren’t inherently ‘wrong’ either, and working with plants isn’t inherently ‘right’. Let’s talk options.
I’ve got a few specific suggestions for you below, and I want to ask you to keep a question in mind- what’s the common denominator between working with the following plants?
I get my Meadowsweet from Avena Botanicals, and there are many other fine herbal makers out there as well. One dropper (a squeeze to the bulb on top fills the dropper about half way, this is what we want) by mouth when you take the NSAIDS.
As a bonus, Meadowsweet has its own pain relieving parts like salicylic acid, so it’ll add to the pain relief you feel.

Great! Treating the root causes is a favorite theme in herbalism. First, and I can’t stress this enough, you’ve got to look at your long-term inputs. Taking care with what you choose to put into your body will reduce the inflammation load your body has to deal with. This way, when something else comes up that causes inflammation, you’ve got more resources at your disposal to help it.

It helps to take a hot second and understand that inflammation is not only a normal process in the body, but a helpful one. Your body is essentially mounting an immune response to overcome a perceived threat, and sometimes that response is out of proportion and/or won’t shut off like it’s supposed to. This is when inflammation becomes a “problem”, and when the rest of your choices can support a more appropriate response.
This is also a good time to bring up the concept of a ‘health team’. If you’re not equipped to do all this on your own, working with a good nutritionist, dietician, and/or a food based therapist might be perfect for you.

Turmeric is classic with aches and pains, and indeed it’s very helpful. It acts similarly to a steroid, bringing down inflammation systemically, and can be ingested easily as a regular food for regular support- IF you take a tiny bit of care when cooking with it. Here’s a study showing that Turmeric’s solubility in water increased 12x when it was heated, and another that its bioavailbility (how well we humans can absorb and use it) increased by 2,000% when mixed with black pepper. Historically it’s also always been cooked with a fat and is considered fat soluble. Moral of the story- cook Turmeric with black pepper and a bit of fat (including milk) for the best effects, and do it daily!
I sneak Turmeric into anything long-cooking like tomato sauces and stews, which I make frequently. The recently-popular Golden Milk recipes you can find all over the internet are tasty too, and check all the boxes for increasing efficacy.
Ginger is also helpful with pain, though this might be surprising if you think of Ginger as hot and fiery, like the inflammation is. However, spices like Ginger and Peppers increase circulation with their heat, and this can bring inflammation down by either speeding up the healing process the inflammation is trying to accomplish, or by moving more fluid through a site and washing away the pro-inflammation signals and delivering the end-inflammation ones that were stuck in the traffic jam caused by swelling.
You can work with Ginger internally (it’s yummy in a lot of the same places Turmeric is, and also on its own), and you can work with it topically too. For example, you grate it onto a cloth so the juice soaks in, and place this poultice (simply a wet, topical application of plants) right on an area of the skin that needs more circulation. You can do the same with Turmeric but be aware the skin will stain yellow, and the oils in Peppers are typically too strong for topical use.
Another problem I want to bring up is topical nerve pain. St. John’s Wort infused in oil, like this one from Barefoot Botanicals, is a good choice. SJW will help heal the nerves that are on and near the surface of your skin- mostly, in my experience, this happens with back injuries either at the site or down a nerve pathway along a leg.
There’s never a “best herb for [fill in your complaint]”. There’s only how the plant interacts with us, and whether we can work with both the plant actions and our responses to them to impact what we’re trying to do.
Look at it this way- pharmaceuticals get in the driver’s seat and steer the bus for us- and sometimes that’s great, that’s perfect, that’s exactly what we need. On the other hand, plants are like good friends or therapists, nudging and guiding and helping us get where we want to be but without forcing us. The beauty is that, as humans, we’re responsible for choosing among these methods, separately or combined.